she appear bfrd a crowd of more than 3,000 as part of alum david letterman's professional workshop and lecture series an got a rousing welcome. >> ladies and gentlemen, do me a favor. please welcome oprah winfrey. [ cheers and applause ] >> everybody is on the journey, the adventure of your life is to discover what your journey is. >> reporter: dave was a big draw too, but it was oprah, students were looking to for inspiration. and this media icon from humble beginnings didn't disappoint with nugget after nugget of powerful insights. >> if there was a number one reason why you've been able to be successful in your life, for me it is listening to that still small voice. it has guided me in every major decision. >> right. >> and when i get in big trouble is when i don't pay attention, i don't heed it. i really did believe that there was a power greater than myself. that that ruling my life. i really -- i really did believe. >> jenna coy, abc news. muncie. >> i love that they came together after that long, long feud, which broke a few years ago. >> 2005. >> and they both came from humble